Fibroblast growth factor 8 (FGF-8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF-8 functions broadly to promote cell proliferation, differentiation, and migration. Overexpression of FGF-8 increases tumor growth and angiogenesis. Human and mouse FGF-8 proteins show 100% homology.
Bioactivity Assay:NR6R 3T3 cell proliferation; ED50 =150 ng/mL; Bioactivity =6.7 x 10^3 units/mg