Corning ECM mimetic surfaces and substrates contain biologically active, synthetic, animal-free peptides that have been rationally designed to mimic the cell attachment motifs of native ECM proteins. The peptides enable optimal cell binding and signaling in a broad range of serum-free, xeno-free, and animal-free media formulations, supporting the propagation and differentiation of a range of stem, progenitor, and primary cell types.Corning PureCoat cultureware is coated with biologically active, synthetic, animal-free peptides that are covalently linked to a proprietary surface to provide a highly consistent, cost-effective alternative to self-coated extracellular peptides. The proprietary covalent linkage orients the peptides for optimal binding and signaling.