IL-2C126S is an immunomodulatory cytokine that is produced by lymphocytes. IL-2C126S signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. • Stimulates the proliferation and differentiation of B cells, natural killer (NK) cells, monocytes, and macrophages • Promotes proliferation and differentiation of CAR T cells, T cells, and NK cells • Activates and expands T cells and NK cells from peripheral blood The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Bioactivity Assay:Proliferation of CTLL- 2; ED50 =3 ng/mL; Bioactivity = 1.8 x 10^4 IU/µg