β-estradiol is a potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation. β-Estradiol is used to study cell differentiation and transformations (tumorigenicity). The pharmacology and HPLC determination of β-Estradiol…

n-Octyl-β-D-Glucopyranoside is a non-ionic detergent for membrane protein. n-Octyl-glucoside is a non-ionic alkyl-glucoside detergent commonly used in the solubilization of membrane proteins and phospholipids. n-Octyl-glucoside has been used at a molar dependant ratios for the…

Synonyms: 1,2,3-Tricaprinoylglycerol, 1,2,3-Tridecanoylglycerol, Glycerol tricaprate, Glycerol tris(decanoate), Tridecanoin, Glyceryl tridecanoate, 1,2,3-Tridecanoyl-rac-glycerol, Glyceryl tridecanoate, Tri-N-Caprin Molecular Formula: C₃₃H₆₂O₆

β-NAD is one of the biologically active forms of nicotinic acid. Coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols Inhibitory neurotransmitter in visceral smooth muscle Acts as a hydrogen acceptor, forming NADH …

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…

Coenzyme A is an essential cofactor in enzymatic acetyl transfer reactions. Facilitates removal of lipid peroxides by increasing mobilization of fatty acids Promote repair of plasma membranes by activating phospholipid synthesis The principal biologically active forms of pantothenic…

Histamine Diphosphate Monohydrate is potent vasodilater. Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Bovine Transferrin is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. Transferrin (HOLO) is an iron-rich product supplied as a heat-treated, lyophilized powder.

Stachyose Tetrahydrate

Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. Con A exists as a dimer below pH 5.0 and and at pH >7 it exists as a tetramer. Con-A is not a glycoprotein. The monomeric molecular weight of Con-A is 25,500. Con-A does not…

This is an ultrapure NAD, chromatographically purified to remove trace inhibitors. β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state.…

Naloxone is specific and competitive opiate antagonist at mu, kappa, delta and sigma receptors; it blocks the action of sigma-agonists at opioid sites. It displaces morphine and other opiate agonists from the opiate receptor. It is more potent than Nalorphine and is also an effective antagonist for…

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin,…

Guanosine-5'-triphosphate, a purine nucleotide, is required as a coenzyme for protein biosynthesis in a cell-free system. Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR)…

Isoleucine provides a source of nitrogen for transport to the liver and kidney.

8-Anilino-1-naphthalene Sulfonic Acid is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle…

Vitamin D3 is the naturally occuring form of vitamin D3. Vitamin D3 mediates intestinal calcium absorption, bone metabolism, and probably muscle activity. It acts as a hormone precursor since it requires two stages of metabolism: first to 25-hydroxycholecalciferol; then to 1 ,…

Pectolyase Y-23 is a highly purified maceration enzyme from Aspergillus niger. It contains two types of pectinase such as endopolygalacturonase and endo-pectin lyase in high activity. Included is a maceration stimulating factor which stimulates tissue maceration by both pectinases. Unit Definition:…

3,3-Diaminobenzidine Tetrahydrochloride is a reagent used in colorimetric analysis of Se and other metals. DAB is utilized in many applications for visualization of peroxidase activity. In the peroxidase reaction DAB serves as a hydrogen donor in the presence of peroxide; the oxidized DAB forms…

Collagenases degrade native helical collagen fibrils. The substrate, collagen, is the major fibrous component of animal extracellular connective tissue: skin, tendon, blood vessels, bone, etc. True collagenase may cleave simultaneously across all three chains or attack a single strand. The enzyme…

Vitamin K is a group of structurally similar, fat-soluble vitamins. Vitamin K1 is used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.

Chicken egg albumin is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated-glycoprotein. From the amino acid sequence, the peptide portion of the molecule consists of 385 residues and has a molecular weight of 42.7 kDa. A phosphorylated glycoprotein which is…

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

Fluorescent Brightner 28 is a colorless organic compound that fluoresces (clear bluish) under ultraviolet radiation. It is related structurally to Fluorescent Brightner 9 (Calcofluor White MR) which was used by Jefferies and Belcher and Maeda and Ischida in plant tissue studies. Fluorescent…

Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

Albumins are a group of acidic proteins which occur in the body fluids and tissues of mammals and in some plant seeds. Serum and plasma albumin is carbohydrate free and comprises 55-62% of the protein present. However, only about 40% of the total albumin in the body is in the circulating plasma at…

Trypsin consists of a single chain polypeptide of 223 amino acid residues. Member of the serine protease family Dissolves blood clots in its microbial form Treats inflammation in its pancreatic form Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues.…

3,3',5,5'-Tetramethylbenzidine is suitable as peroxidase substrate for use in ELISA procedures. The substrate produces a soluble end product that is pale blue in color and can be read spectrophotometrically at 370 or 620-650 nm. The TMB reaction may be stopped with 2 M H2SO4 (resulting in a…

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is used as emollient. Small amounts of oleic acid are used as an excipient in…

Doxycycline is an antibiotic  against gram-positive and gram-negative bacteria. More active biologically than the corresponding 6b-epimer hydrochloride. Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in…

Fetuin is a protein containing 12 Cys residues, all involved in disulfide bridges. The composition of bovine fetuin (weight %) is polypeptide 74%, hexose 8.3%, hexosamines 5.5%, and sialic acid 8.7%. Fetuin bovine is a protein with the ability to bind to the insulin receptor and inhibit insulin…

Adenosine 5′-diphosphate is a P2Y receptor agonist. Adenosine 5′-diphosphate has been used to study the release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD+) in the rat brain. Adenosine 5′-diphosphate has also been used to…