Application: UHPLC/MS Analysis of Kratom and its Metabolite on Ascentis® Express C18, 2 mum Legal Information: Ascentis is a registered trademark of Sigma-Aldrich Co. LLC

LiChrospher® Si 60 is a versatile HPLC spherical silica sorbent with a pore diameter of 60A and a particle size of 5µm  for normal phase chromatography: This  sorbent is packed into a LiChroCART® 125-4 HPLC cartridge. The connection to the HPLC system is being…

YMC-Triart Diol-HILIC is a HILIC (hydrophilic interaction chromatography) column based on an organic/inorganic hybrid particle synthesized with dihydroxypropyl groups. Triart Diol-HILIC is ideal for a separation of polar and hydrophilic compounds that are not retained by reversed-phase (C18, C8,…

SMT manufactures the most reliable silica based packing materials available in the market today. When silica is used as the stationary phase, the functional groups involved in separation are the surface silanols. However, metal impurities in silica may provide additional sites of interaction for…

The Phenyl-Hexyl phase has unique selectivity arising from solute interaction with the aromatic ring and its delocalized electrons. It is complementary (orthogonal) to both C18 and RP-Amide phases because of this unique aromaticity. The Phenyl-Hexyl phase also tend to exhibit good shape…

ZORBAX Eclipse Plus HPLC columns are the ideal first choice for method development of all samples. Available in C18, C8, Phenyl Hexyl and PAH. Agilent Technologies products are intended for sale/shipment within the US only. International customers should contact their local Agilent…

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties: Totally spherical particle shape Outstanding surface microstructure High pressure stability Low metal content NUCLEODUR® as a state-of-the-art silica…

Protect Your Investment - Hamilton guard columns protect analytical, semi-prep and preparative HPLC columns. They also remove particulate contaminants and highly adsorptive compounds from samples, prolonging column life. The designs are modular and cartridge replacement is easy and tool-free. …

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties: Totally spherical particle shape Outstanding surface microstructure High pressure stability Low metal content NUCLEODUR® as a state-of-the-art silica…

LiChrosorb® RP-8 is a reliable irregular shaped silica gel carriers with reversed phase properties. It is well suited for the separation of neutral, acidic and weak basic compounds.This sorbent is packed into a Hibar® 125-4 HPLC column. For mounting of a LiChroCART® 4-4 guard column,…

O Series SMT SAM-C8 phase with the highest functional ligand coverage confirmed with carbon analysis results of 12% carbon load. In these series, a very high density of the functional ligand, octyl molecule or C8, is achieved through meticulous mixture of the C8 with proprietary spacer…

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure Wide acceptance as routine packings for very different fields of chromatography One of the first spherical silicas used in HPLC Developed in the early seventies, it became a…

Purospher® STAR NH2 HPLC columns are amino-bonded high-purity silica columns primarily for carbohydrate analysis. The particular benefits of these columns are the very high separation efficiency and the absence of metallic impurities, giving consistent symmetrical peaks.

Widely considered the premium columns for analyzing biopolymers by GFC, TSKgel SWXL columns feature high pore volume per unit column volume, low sample adsorption and excellent column efficiency, all contributing to unsurpassed sample resolution. With 5mum particles and 125Å pores, TSKgel G2000SWXL…

Application: Discovery® HS C18 HPLC column may be used for the separation of cefdinir and cefixime in plasma samples, followed by their analysis and detection using reversed-phase high performance liquid chromatography coupled with ultraviolet detector. Legal Information: Discovery is a…

Discovery® HS C18 HPLC column (L x I.D. 5 cm x 2.1 mm) is commonly found to be stable under acidic and basic conditions. Legal Information: Discovery is a registered trademark of Sigma-Aldrich Co. LLC

The Ascentis family of columns is the fourth generation of HPLC column technology from Supelco scientists. Ascentis columns are bonded on high purity, 100 Angstrom silica including 3, 5, and 10 micron particle size. Columns are designed for small molecule applications and are scalable from micro…

SMT WCX Bulk Packings are silica-based Weak Cation eXchange packing materials developed for separation of cationic compounds. SMT WCX Bulk Packings consist of chemically attached hydrophilic surface derivatized to form carboxylic acid functionality. The technique of SAM is used in the bonding…

Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine. Legal Information: Discovery is a registered trademark of Sigma-Aldrich Co. LLC

TSKgel® Butyl-NPR columns are not as hydrophobic, i.e., less retentive, than Phenyl-5PW and Ether-5PW HIC columns. They are the best choice for high speed separations and provide excellent recovery even for more hydrophobic proteins. The non-porous resin requires lower sample loading and leads to…

SMT-WAX Bulk Packings are silica-based Weak Anion eXchange packing materials developed for separation of anionic compounds. SMT WAX Bulk Packings consist of chemically attached hydrophilic surface derivatized to form polyethyleneimine functionality. The technique of SAM is used in the bonding…

For the connecting of still available CC cartridge columns and CC guard columns we offer the guard column holder.

Discovery® RP-AmideC16 HPLC Column consists of a stationary phase made up of high-purity C16-silica that includes a polar-embedded amide function attached to the silica surface with a propyl group. Application: Discovery® RP-AmideC16 HPLC column may be used for the separation of: •Phenolic…

Application: TSKgel® UP-SW3000 HPLC Column may be used for the separation of: •Free payloads and related species from antibody drug conjugates (ADCs) and their aggregates, during their determination by using 1-dimensional (1D) gradient size exclusion chromatography (SEC). •Protein…

TSKgel DNA-NPR columns are packed with 2.5 micron, non-porous, high efficiency, hydrophilic polymer beads which are surface modified with a weak anion exchanger. Because NPR columns contain non-porous particles, binding capacity is low compared to porous columns with the same ligand functionality.…

Discovery BIO Wide Pore C5 was designed for the efficient and reliable separation of proteins and peptides, especially hydrophobic peptides, by RP- HPLC. Long-chain phases, like C8 or C18, are often too hydrophobic for proteins and can cause excessively long retention time or even irreversible…

The YMC-Pack C4 stationary phase surface hydrophobicity is lower than that of both ODS and C8 Retention times of samples on YMC-Pack C4 therefore tend to be shorter than those on ODS or C8. Separation characteristics of YMC-Pack C4 also differ from those of ODS. YMC-Pack C4 achieves better…

Application: UHPLC Analysis of Sunscreens on Ascentis® Express RP-Amide, 2.7 mumU/HPLC Analysis of Phenolic Acids on Ascentis® Express RP-Amide, 2.7 mum Legal Information: Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

Application: UHPLC Analysis of Sunscreens on Ascentis® Express RP-Amide, 2.7 mumU/HPLC Analysis of Phenolic Acids on Ascentis® Express RP-Amide, 2.7 mum Legal Information: Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

YMC-Pack C4 (Butyl) columns are less hydrophobic than C8 or C18 packings, and generally utilize more aqueous eluents than either of these reversed phase column types. When compared to C8 and C18 columns using the same eluent, C4 columns show significantly shorter retention for non-polar compounds.…

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure Wide acceptance as routine packings for very different fields of chromatography One of the first spherical silicas used in HPLC Developed in the early seventies, it became a…

In areas like drug discovery where target compounds are increasingly polar, it is critical to have a reversed-phase column that performs well under aqueous conditions. Retention is critical, but cannot come with troublesome secondary interactions. From the collapse-resistant pore structure of…