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Biologically Active Small Molecules, Cayman Chemical, 937039-45-7, Bottle, Glass, Clear

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Bottle, Glass, Clear 937039-45-7 Cayman Chemical Biologically Active Small Molecules

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Pimelic Diphenylamide 106

Cayman Chemical

A slow, tight-binding inhibitor of class I HDACs, progressively binding HDACs and remaining bound after wash-out; inhibits class I HDACs (IC₅₀ = 150, 760, 370, and 5,000 nM for HDAC1, 2, 3, and 8, respectively) but not class II HDACs (IC₅₀ > 180 µM for HDAC4, 5, and 7).

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