Biologically Active Small Molecules, Cayman Chemical, 70476-82-3, Bottle, Glass, Clear

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  • An anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation; human HIV-1 integrase (IC50 = 3.8 μM); exported from cells in an ATP- and glutathione-dependent manner by MRP1.