Biologically Active Small Molecules, Cayman Chemical, 472981-92-3, Bottle, Glass, Clear

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    A selective TRPV1 antagonist widely used in pain research; inhibits capsaicin-evoked Ca2+ influx with an IC50 value of 0.7 μM in cultured trigeminal ganglion neurons; reduces capsaisin-induced nociceptive responses in a model of pain and suppresses tolerance to the analgesic effects of chronic…