Biologically Active Small Molecules, Cayman Chemical, 415903-37-6, Bottle, Glass, Clear

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  • Cayman Chemical

    A potent and selective antagonist of the EP4 receptor (Ki = 13 and 20 nM for human and rat EP4, respectively); inhibits PGE2-evoked elevation in intracellular cAMP in cells and, in vivo, reduces thermal hyperalgesia induced by intraplantar injection of PGE2.