Synonyms: 4-(N-Ethyl-N-phenylamino)-1,2 dimethyl-6-(methylamino) pyrimidinium chloride; ICI-D7288; N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine hydrochloride; ZD 7288
Molecular Formula: C15H20N4 · HCl · xH2O
Linear Structural Formula: C15H20N4 · HCl · xH2O
MDL Number: MFCD16879001
Purity: >=98% (HPLC)
Storage: 2-8C
Application: ZD7288 hydrate has been used as Ih blocker to study its effect on neocortical tissue. It has been used as hyperpolarization-activated and cyclic nucleotide-gated (HCN)-channel blocker to test the involvement of HCN channels in the phototransduction pathway.
Biochem Physiol Actions: ZD7288 can block hippocampal synaptic plasticity.