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A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3β complex and promotes the degradation of β-catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 µM.

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Product Detail
Thomas No.
C831H31
Mfr. No.
13596-1
Description
XAV939-1 mg
CAS Number
284028-89-3
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
UN Number
UN2811
list price/quantitytotal
$0.00
Thomas No.
C831H32
Mfr. No.
13596-5
Description
XAV939-5 mg
CAS Number
284028-89-3
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
UN Number
UN2811
list price/quantitytotal
$0.00
Thomas No.
C831H33
Mfr. No.
13596-10
Description
XAV939-10 mg
CAS Number
284028-89-3
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
UN Number
UN2811
list price/quantitytotal
$0.00
Thomas No.
C831H34
Mfr. No.
13596-25
Description
XAV939-25 mg
CAS Number
284028-89-3
Packaging Size
25 mg
Packaging Type
Bottle, Glass, Clear
UN Number
UN2811
list price/quantitytotal
$0.00
$0.00 (0 Items)
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