Synonyms: XOD; Xanthine:oxygen oxidoreductase
CAS Number: 9002-17-9
MDL No.: MFCD00082145
Storage: 2-8C
Enzyme Commission (EC) Number: 1.17.3.2.
EC Number: 232-657-6
UNSPSC Code: 12352204
General description: Formerly E.C. 1.1.3.22
Biochem/physiol Actions: Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c.
Biochem/physiol Actions: Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
Physical form: Suspension in 2.3 M (NH4)2SO4 containing 1 mM sodium salicylate
Unit Definition: One unit will convert 1.0 mumole of xanthine to uric acid per min at pH 7.5 at 25 C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.
Analysis Note: Protein determined by biuret
RTECS: RQ8455000
RIDADR: NONH for all modes of transport
WGK Germany: 3