Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Venlafaxine Hydrochloride is the hydrochloride salt of venlafaxine, a non-tricyclic antidepressant and serotonin-norepinephrine-dopamine reuptake inhibitor.
Synonyms: Venlafaxine hydrochloride; (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride; Effexor
Molecular Formula: C17H27NO2 · HCl
Molecular Weight: 313.86
Linear Structural Formula: C17H27NO2 · HCl
MDL Number: MFCD03658865
Application: Venlafaxine Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high performance liquid chromatography technique. It is also used as a secondary pharmaceutical standard for the determination of venlafaxine in pharmaceutical formulations using liquid chromatography technique.
Biochem Physiol Actions: Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or alpha-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.