Dehydrated culture medium with vegetable peptones as a non-animal origin alternative to Soybean Casein Digest Medium (SCDM), also referred to as Tryptic Soy Broth. The Granulated media is cold filterable and gamma-irradiated for the microbiological validation of aseptic filling processes (media fill test or aseptic process simulation. The product is gamma-irradiated and triple-bagged allowing for safe introduction into controlled areas. Cold filterability is achieved by extensive testing comprising raw materials, pre-production samples, in-process and end product control. The formulation contains peptones of nonanimal origin instead of the recommended peptones.
Synonyms: TSB, CASO, Casein Soybean Digest Broth, TSB non animal origin, SCDB
Application: The broth is suitable for media fill tests according to the recommendations of the "FDA Aseptic Guide" in aseptic production lines. The exclusive use of raw materials of non-animal origin allows the elimination of a potential contamination risk with TSE/BSE.
Legal Information: GRANUCULT is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Mode of action: The microbiological performance of TSB non-animal origin is equivalent to the standard TSB. The dehydrated culture medium is gamma-irradiated with 48-76 kGy. The intensity of irradiation guarantees that Bacteria, spores, viruses and mycoplasma are destroyed. It provides a higher level of security with regard to radiation-resistant microorganisms than other commercially available products.