Trifluoroacetic anhydride, ReagentPlus(R), >=99%

Synonyms: TFAA

CAS Number: 407-25-0

Formula: C4F6O3

Formula Weight: 210.03

Linear Formula: (CF3CO)2O

MDL No.: MFCD00000416

Purity: >=99%

Boiling Point: 39.5-40 C(lit.)

Melting Point: -65 C (lit.)

Density: 1.511 g/mL at 20 C(lit.)

Refractive Index: n20/D 1.3(lit.)

Beilstein Registry Number: 746197

EC Number: 206-982-9

UNSPSC Code: 12352100

Application: For the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for GC analysis. Also used in the oxidation of aldehydes to acids, esters, or amides. Trifluoroacetic anhydride can undergo reaction with deoxyguanosine in pyridine to give the corresponding 6-substituted-2'-deoxyguanosine derivatives. It can also react with urea-hydrogen peroxide complex to generate peroxytrifluoroacetic acid, which can convert aldoximes to nitroalkanes.