Synonym: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan, Triclosan
CAS Number: 3380-34-5
Empirical Formula (Hill Notation): C12H7Cl3O2
Molecular Weight: 289.54
Beilstein Registry Number: 2057142
EC Number: 222-182-2
MDL Number: MFCD00800992
Analysis Note
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application
A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products. Because of its low antigenicity, irgasan is also a component of many antibacterial consumer products.
Biochem/physiol Actions
Irgasan is a broad spectrum antimicrobial agent. It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.
General Description
Certified Fluka® pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Other Notes
This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (AClass Cert AT-1467), ISO GUIDES 34:2009 (AClass Cert AR-1470).
Legal Information
FLUKA is a registered trademark of FLUKA GmbH
Grade: certified reference material
Pharmacopeia Traceability: traceable to USP 1682206