trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain ß-oxidation defect in newborns.
Synonyms: (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-tetradecen-1-yl]oxy]-1-propanaminium inner salt; trans-2-Myristenoyl-L-carnitine; C14:1-Carnitine
Molecular Formula: C21H39NO4
Molecular Weight: 369.54
Linear Structural Formula: C21H39NO4
Purity: >=95.0% (LC/MS)
Storage: -20C
Application: trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:
•Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
•Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).