Thyroid cancer is the most prevalent endocrine carcinoma, with a rapidly increasing occurrence in many countries. Human models of differentiated thyroid cancer are highly valuable for assessing the pathways and mechanisms that contribute to thyroid carcinogenesis. References:1. Davies L, Welch HG (2006). Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 295(18): 2164-2167.2. Pilli T, et al. (2009). Potential utility and limitations of thyroid cancer cell lines as models for studying thyroid cancer. Thyroid 19(12): 1333-1342.3. Meireles AM, et al. (2007). Molecular and genotypic characterization of human thyroid follicular cell carcinoma-derived cell lines. Thyroid 17(8): 707-715.4. Rudzińska M, et al. (2014). The role of podoplanin in the biology of differentiated thyroid cancers. PLoS One 9(5): e96541.5. Tanaka J, et al. (1987). Establishment and biological characterization of an in vitro human cytomegalovirus latency model. Virology 161(1): 62-72.6. Ishizaka Y, et al. (1989). Presence of aberrant transcripts of ret proto-oncogene in a human papillary thyroid carcinoma cell line. Jpn J Cancer Res 80(12): 1149-1152.
Synonyms: TPC1
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