Antigen: peptide from human TLR1 within the region of amino acids 400-450
Host: rabbit
Cross Reactivity: (+) human, mouse, and rat TLR1
Application(s): FC (intracellular and cell surface) and WB
TLR1 interacts with TLR2 and coexpression of TLR1 and TLR2 enhances the NF-kB activation in response to a synthetic lipopeptide. Together, they recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.