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MilliporeSigma

Toceranib >=98% (HPLC)

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Synonyms: 5-[(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(pyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide; PHA-291639; SU-11654; SU11654

Molecular Formula: C22H25FN4O2

Molecular Weight: 396.46

Linear Structural Formula: C22H25FN4O2

Purity: >=98% (HPLC)

Storage: room temp

Biochem Physiol Actions: Toceranib (SU11654) is a protein tyrosine kinase inhibitor that selectively targets stem cell factor receptor c-kit, including all forms of mutant Kit, as well as PDGFR and VEGFR. Toceranib exhibited Ki values of 5 nM for PDGFR and 6 nM for VEGFR. Toceranib phosphate is approved for use in mast cell cancer in dogs.

Legal Information: Sold for research purposes under agreement from Pfizer Inc.

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Product Detail
Thomas No.
CHM02U262
Mfr. No.
PZ0338-5MG
Description
PZ0338-5MG, Toceranib >=98% (HPLC)
CAS Number
356068-94-5
list price/quantitytotal
$0.00
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