Synonyms: L-Arginyl-L-seryl-L-threonyl-L-alpha-aspartyl-L-leucyl-L-prolylglycyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-L-threonyl-L-histidyl-L-tyrosyl-L-threonyl-L-isoleucyl-L-threonyl-L-isoleucyl-L-arginylglycyl-L-valyl-L-cysteine trifluoroacetate salt; RSTDLPGLKAATHYTITIRGVC trifluoroacetate salt
Molecular Formula: C103H173N31O31S · xC2HF3O2
Linear Structural Formula: C103H173N31O31S · xC2HF3O2
Purity: >=95% (HPLC)
Storage: -20C
Biochem Physiol Actions: TNIIIA2 is a Tenascin-C driven proadhesive peptide that potently activates beta1-integrins including alpha5beta1. TNIIIA2 forces hematopoietic tumor cell lines to adhere via VLA-4 to fibronectin, which induces apoptosis. It appears that TNIIIA2 uses Syndecan-4 as a receptor.