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MilliporeSigma

Tizoxanide >=98% (HPLC)

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Synonyms: 2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide; 2-Hydroxy-N-(5-nitrothiazol-2-yl)benzamide; Desacetyl-NTZ; Desacetyl-nitazoxanide; NSC 697856; NTZ metabolite; Nitazoxanide metabolite; TIZ

Molecular Formula: C10H7N3O4S

Molecular Weight: 265.25

Linear Structural Formula: C10H7N3O4S

MDL Number: MFCD07484970

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: Tizoxanide (TIZ) is the active metabolite of the broad-spectrum parasiticidal drug nitazoxanide (NTZ), a noncompetitive inhibitor against bacterial pyruvate-ferredoxin oxidoreductase (PFOR Ki 2 to 10 muM). NTZ deacetylates rapidly to TIZ in plasma (t1/2 ~6 min at 37C in human plasma) and in the presence of liver microsomes. NTZ is also reported to exhibit antiviral activity against Hepatitis C, Norovirus, Paramyxovirus, Influenza, Vaccinia, and Zika.

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Product Detail
Thomas No.
CHM02U660
Mfr. No.
SML2837-5MG
Description
SML2837-5MG, Tizoxanide >=98% (HPLC)
CAS Number
173903-47-4
list price/quantitytotal
$0.00
Thomas No.
CHM02U661
Mfr. No.
SML2837-25MG
Description
SML2837-25MG, Tizoxanide >=98% (HPLC)
CAS Number
173903-47-4
list price/quantitytotal
$0.00
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