Synonyms: (S)-N-[3-(beta-D-glucopyranosyloxy)-1,2-dimethoxy-10(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo [a] heptalen-7-yl] acetamide; 2-Demethoxy-2-glucosidoxythiocolchicine
Molecular Formula: C27H33NO10S
Molecular Weight: 563.62
Linear Structural Formula: C27H33NO10S
MDL Number: MFCD07995056
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: Thiocolchicoside is a potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist with muscle relaxant, anti-inflammatory, and analgesic activity. Thiocolchicoside has also been found to suppress nuclear factor kappa B ligand (RANKL) activation of NF-KB resulting in suppression of osteoclastogenesis.