Synonyms: TAA; TMA; Thiacetic acid
CAS Number: 507-09-5
Formula: C2H4OS
Formula Weight: 76.12
Linear Formula: CH3COSH
MDL No.: MFCD00004853
Purity: 0.96
Boiling Point: 88-91.5 C(lit.)
Density: 1.065 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.465(lit.)
Storage: 2-8C
Beilstein Registry Number: 1733298
EC Number: 208-063-8
UNSPSC Code: 12352106
Application: Thioacetic acid is a reagent for introduction of the thiol group into organic molecules.
Application: Thioacetic acid (TAA) can undergo:. Enantioselective addition to nitroalkenes to form chiral 1,2-aminothiol derivatives in the presence of a novel sulfinyl urea organocatalyst. This method has been successfully employed in the synthesis of antifungal drug, sulconazole.. Asymmetric Michael addition reaction with chalcones in the presence of a bifunctional amine thiourea catalyst to form synthetically useful thioesters.. Asymmetric 1,6-conjugate addition with para-quinone methides in the presence of a chiral phosphoric acid catalyst to form chiral sulfur-containing diphenylmethane-type compounds.. Conjugate addition to methacrylamides with chiral trans-2,5-disubstituted pyrrolidine auxiliaries to form chiral β-mercaptocarboxylic acid derivatives.
RTECS: AJ5600000
RIDADR: UN 2436 3 / PGII
WGK Germany: 3
Flash Point(F): 51.8 F
Flash Point(C): 11 C
R Codes: 11-34-41-43
S Codes: 9-16-26-36/37/39-45
IOD Codes: F,Xn
Symbol: GHS02, GHS05, GHS06
Signal Word: Danger
Hazard Statements: H225-H301-H317-H318
Precautionary statements: P210-P280-P301 + P310 + P330-P305 + P351 + P338 + P310-P333 + P313-P370 + P378