Thimerosal belongs to the group of alkyl mercury compounds, widely used as a preservative in vaccine formulations. Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Synonyms: Thimerosal; 2-(Ethylmercuriomercapto)benzoic acid sodium salt; Ethylmercurithiosalicylic acid sodium salt; Mercury-([o-carboxyphenyl]thio)ethyl sodium salt; Sodium ethylmercurithiosalicylate
Molecular Formula: C9H9HgNaO2S
Molecular Weight: 404.81
Linear Structural Formula: 2-(C2H5HgS)C6H4CO2Na
MDL Number: MFCD00013062
Melting Point: 234-237 C (dec.) (lit.)
Application: Thimerosal may be used as a pharmaceutical reference standard for the quantification of the analyte in ophthalmic solutions using spectrophotometric technique.
Biochem Physiol Actions: Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na++K+ dependent ATPases.
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.