Synonyms: 2-(5-(4-((Phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid dihydrochloride; 2H-Tetrazole-2-acetic acid, 5-[4-[[(2-phenylethyl)[4-[4-(1-pyrrolidinylmethyl)phenoxy]butyl]amino]methyl]phenyl]-, hydrochloride (1:2); TIP60i
Molecular Formula: C33H40N6O3 · 2HCl
Molecular Weight: 641.63
Linear Structural Formula: C33H40N6O3 · 2HCl
MDL Number: MFCD28396413
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: TH1834 is a cell penetrant, potent and selective histone acetyltransferase (HAT) Tip60 inhibitor that interact with active binding pocket of Tip60. TH1834 induces apoptosis and increased unrepaired DNA damage in breast and prostate cancer cell lines but not control MCF10A cells.