TGF-beta-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-beta superfamily. TGF-beta-I, TGF-beta-II and TGF-beta-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-beta3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-beta3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-beta-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Synonyms: Transforming Growth Factor Beta 3, TGF-Beta-3, TGF-Beta-III
Purity: >98% (SDS-PAGE and HPLC)
Application: Research Sub CategoryGrowth Factors & Receptors