Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.
Synonyms: 3,3',3'',3'''-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol; 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin
Molecular Formula: C44H32N4O4
Molecular Weight: 680.75
Linear Structural Formula: C44H32N4O4
Purity: >=90% (HPLC)
Storage: -20C
Biochem Physiol Actions: Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.