tBuXPhos [2-Di-tert-butylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
Synonyms: 2-Di-tert-butylphosphino-2',4',6'-triisopropylbiphenyl; t-Bu XPhos; tert-Butyl XPhos
Molecular Formula: C29H45P
Molecular Weight: 424.64
Linear Structural Formula: C29H45P
MDL Number: MFCD06411306
Purity: 95%
Melting Point: 148-151 C (lit.); 150 C
Application: tBuXPhos has been used in the preparation of [tBuXPhosAu(MeCN)]BAr4F, a gold catalyst for the intermolecular [2+2] cycloaddition of terminal arylalkynes with substituted alkenes to form functionalized cyclobutenes with high regioselectivity.
Legal Information: Usage subject to Patents: EP 1097158; JP 5758844; CA 2336691