Synonym: 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, Sodium taurocholate hydrate
CAS Number: 345909-26-4
Empirical Formula (Hill Notation): C26H44NNaO7S · xH2O
Molecular Weight: 537.68 (anhydrous basis)
EC Number: 205-653-7
MDL Number: MFCD00150819
PubChem Substance ID: 24900186
Application
Anionic detergent used for protein solubilization.
Taurocholic acid sodium salt hydrate has been used in a study to assess the adsorption of bile acids and salts to vegetable fibrous tissue. It has also been used in a study to investigate a method for determination of conjugated and unconjugated bile salts in serum and jejunal fluid.
General Description
Taurocholic acid sodium salt hydrate is a bile acid with detergent capabilities.
Packaging
1, 5, 25, 100 g in poly bottle; 250 mg in poly bottle
Preparation Note
Synthesized from cholic acid
Biochem/physiol Actions
Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.
Quality Level: PREMIUM
Description: anionic
Assay: ≥95% (TLC)
Mol. Wt.: micellar avg mol wt 2100
Aggregation Number: 4
CMC: 3-11 mM(20-25°C)