This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.Download your certificate at: http://www.sigma-aldrich.com
Synonyms: (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene; trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
Molecular Formula: C26H29NO
Molecular Weight: 371.51
Linear Structural Formula: C6H5C(C2H5)=C(C6H5)C6H4OCH2CH2N(CH3)2
MDL Number: MFCD00010454
Melting Point: 97-98 C (lit.)
Storage: 2-8C
Biochem Physiol Actions: Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
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