Molecular Formula: C11H21NO6
Molecular Weight: 263.29
Linear Structural Formula: C11H21NO6
MDL Number: MFCD17019374
Purity: >=95%
Density: 1.15 g/cm3 (lit.)
Storage: -20C
Application: t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC(R) molecules) for targeted protein degradation.
Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license