Synonym: 3β-Hydroxy-24-ethyl-5,22-cholestadiene, 5,22-Stigmastadien-3β-ol, Stigmasterin
CAS Number: 83-48-7
Empirical Formula (Hill Notation): C29H48O
Molecular Weight: 412.69
Beilstein Registry Number: 2568182
EC Number: 201-482-7
MDL Number: MFCD00003630
PubChem Substance ID: 24899523
Packaging
1 g in poly tube
Preparation Note
Stigmasterol yields clear, colorless solution in chloroform at 50 mg/ml.
Application
Stigmasterol was used as a reference standard in determination of phytosterols in dietary supplements by gas chromatography and in frozen leaf samples of Arabidopsis thaliana by GC/MS.
Biochem/physiol Actions
Stigmasterol is a phytosterol with chemical structure similar to cholesterol. It exhibits anti-cancer, anti-pyretic, anti-inflammatory and immune-modulating effects. Stigmasterol decreases the expression of matrix metalloproteinases and reduced the degradation of cartilage in osteoarthritic rabbits.
Assay: ~95%
MP: 165-167°C(lit.)
Solubility: chloroform: soluble50 mg/ml
Gene Information: human ... POLA1(5422), TOP2A(7153); rat ... Polb(29240)