The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.
Application: Research Sub CategoryCardiovascular DiseaseMetabolic Disorders
Biochem Physiol Actions: Target Sub-Family: TK
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Other Notes: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.