Synonyms: 6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione; CDI 3238389; ML180
Molecular Formula: C20H25ClN4O2
Molecular Weight: 388.89
Linear Structural Formula: C20H25ClN4O2
MDL Number: MFCD05894342
Purity: >=98% (HPLC)
Storage: 2-8C
Application: SR1848 has been used as a liver receptor homolog 1 (LRH-1) inhibitor to study the role of LRH-1 in the regulation of lipopolysaccharide (LPS)-induced proinflammatory cytokines in mice macrophage. It has also been used as an LRH-1 inhibitor to study its effects on activation-induced Fas ligand (FasL) expression in the murine T-cell hybridoma cell line.
Biochem Physiol Actions: The actions of SR1848 might contribute to anti-cancer functionality.