Synonyms: CID 16016685; N-Butyl-N'-(10,11-dihydro-10-methyl-11-oxodibenzo[b,f][1,4]thiazepin-8-yl)urea
Molecular Formula: C19H21N3O2S
Molecular Weight: 355.45
Linear Structural Formula: C19H21N3O2S
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: SR-4995 is a potent and selective ligand of alpha-beta-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling.