SPhos [2-Dicyclohexylphosphino-2′, 6′-dimethoxybiphenyl] is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.
Synonyms: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl; S Phos
Molecular Formula: C26H35O2P
Molecular Weight: 410.53
Linear Structural Formula: C26H35O2P
MDL Number: MFCD05861611
Purity: 95%
Melting Point: 164-166 C (lit.); 165.5 C
Application: Utilized in conjunction with palladium to form a highly active catalyst for C-N bond formation
Legal Information: Usage subject to Patents: US 6307087; EP 1097158; JP 5758844; CA 2336691