Synonyms: 1-(2,5-Dimethoxyphenyl)-4-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-12,3-triazole; LC-1
Molecular Formula: C21H25N3O4S
Molecular Weight: 415.51
Linear Structural Formula: C21H25N3O4S
MDL Number: MFCD14774311
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and in mouse models.