Synonyms: 2-Pyridinesulfinic acid; Sodium salt; Willis 2-pyridylsulfinates H
Molecular Formula: C5H4NNaO2S
Molecular Weight: 165.15
Linear Structural Formula: C5H4NNaO2S
Purity: >=95%
Melting Point: 292 C
Application: This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.
Other Notes:
•Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
•Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides