Synonyms: BMS-387032; N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide
Molecular Formula: C17H24N4O2S2
Molecular Weight: 380.53
Linear Structural Formula: C17H24N4O2S2
MDL Number: MFCD09833875
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: SNS-032 (BMS-387032) is a selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9 that regulate the cell cycle and transcription. It has IC50 values of 38 nM for Cdk2, 62 nM for Cdk7, and 4 nM for Cdk9. SNS-032 was in clinical trials for a variety of cancers including chronic lymphocytic leukemia (CLL) and multiple myeloma (MM).