SnAP (Sn amino protocol) reagents have been developed by Professor Dr. Jeffrey Bode and co-workers. (These reagents are useful for the preparation of medium-ring (6-9 membered) saturated N-heterocycles, including bicyclic and spirocyclic structures.) SnAP reagents are stable and easy to handle in laboratories. They can be prepared from simple raw materials.
Synonyms: tert-butyl 4-amino-4-(((tributylstannyl)methoxy)methyl) piperidine-1-carboxylate
Molecular Formula: C24H50N2O3Sn
Molecular Weight: 533.38
Linear Structural Formula: C24H50N2O3Sn
Storage: -20C
Application: SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode Research Group
Other Notes: Technology spotlight: SnAP Reagents Professor product portal: Jeffrey Bode Research GroupSnAP Reagents for the Synthesis of Piperazines and MorpholinesSnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydesSnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-HeterocyclesBespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles