Synonyms: 2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide
Molecular Formula: C16H15FN2O4
Molecular Weight: 318.3
Linear Structural Formula: C16H15FN2O4
MDL Number: MFCD02219567
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 muM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.