Z-Val-Ala-Asp fluoromethyl ketone, powder, >=90% (TLC)

Synonyms: Z-VAD-FMK, Non-methylated

Formula: C21H28FN3O7

Formula Weight: 453.46

Linear Formula: C21H28FN3O7

MDL No.: MFCD03452883

Purity: >=90% (TLC)

Storage: -20C

UNSPSC Code: 12352200

Features and Benefits: This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Amino Acid Sequence: Z-Val-Ala-Asp-OMe-FMK

Biochem/physiol Actions: Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).