Synonyms: 3-Chloro-4-(3-chloro-2-nitrophenyl)pyrrole
MDL No.: MFCD00865605
Purity: >=98% (HPLC)
Storage: -20C
EC Number: 213-812-7
UNSPSC Code: 12352200
Biochem/physiol Actions: Pyrrolnitrin blocks the terminal electron transport between succinate or reduced NADH and coenzyme Q. In mitochondria preparations of S. cerevisiae, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cythochrome C reductase, and NADH-cytochrome C reductase. Pyrrolnitrin is involved in many cellular processes such as oxidative stress, electron transport, DNA and RNA synthesis.
Specificity: The purified antibiotic has strong antifungal activity and is less efficient against bacteria or yeast.
RTECS: UX9450000
RIDADR: NONH for all modes of transport
WGK Germany: 2
R Codes: 36/37/38
S Codes: 26-36
IOD Codes: Xi
Symbol: GHS07
Signal Word: Warning
Hazard Statements: H315-H319-H335
Precautionary statements: P261-P305 + P351 + P338