Synonyms: PKD3; Protein Kinase C nu
MDL No.: MFCD07371119
Purity: >=75% (SDS-PAGE)
Storage: -70C
UNSPSC Code: 12352200
Application: Kinase activity is measured as the molar amount of phosphate incorporated into the CREBtide substrate peptide (KRREILSRRPSYR) per minute per mg protein at 30 C using a final concentration of 50 muM [32P] ATP.
Biochem/physiol Actions: PKCnu, also known as PKD3, is a member of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCnu is an important physiologic target of the B-cell receptor (BCR) and exhibits activation upon BCR engagement.
Physical form: Solution of 5 mug in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol