Synonym(s): PDGF−AA
Purity: ≥98% (SDS-PAGE and HPLC)
Physical form: Sterile-filtered through a 0.2 μm filter. Lyophilized with no additives.
Analysis Note: The biological activity is measured by the dose-dependent stimulation of thymidine uptake by BALB/c 3T3 cells.
Other Notes: Homodimer of the A chain of human PDGF.
Storage: −20°C
Biochem/physiol Actions: PDGF is believed to play an essential role in the cellular response to tissue injury, both as a stimulant of mesodermal cell growth and activity and as a chemoattractant to other cells involved in the repair process.
Empirical Formula (Hill Notation): C7H9N