Synonyms: Protein Kinase D2
MDL No.: MFCD07371065
Purity: >=70% (SDS-PAGE)
Storage: -70C
UNSPSC Code: 12352200
Application: Kinase activity is measured as the molar amount of phosphate incorporated into the CREBTIDE substrate peptide (KRREILSRRPSYR), per minute per mg protein at 30 C using a final concentration of 50 muM [32P] ATP.
Biochem/physiol Actions: PKD2 is a novel phorbol ester- and growth factor-stimulated serine/threonine kinase that contains two cysteine-rich motifs at the N terminus, a pleckstrin homology domain, and a catalytic domain. The PKD family of enzymes have been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation.
Physical form: Solution of 50 mul in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25Â mM dithiothreitol (DTT), 0.1 mM EGTA, and 30% glycerol.