Synonyms: DXS11 79 E; PRKCl
Purity: >=70% (SDS-PAGE)
Activity: activity: 564-764 nmol/min·mg
Storage: -70C
UNSPSC Code: 12352200
General description: PKCι (protein kinase C ι) belongs to the protein kinase C family.
Biochem/physiol Actions: Protein kinase C ι (PKCι) is involved in Ras signaling. In colonic epithelium, it is an important regulator of oncogenic Ras. Transgenic mice which are constitutively expressing PKCι are at high risk of carcinogen-mediated colon carcinogenesis.
Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
RIDADR: NONH for all modes of transport
WGK Germany: 1