Phosphoinositide 3-kinase p110gamma human, >=95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution

Synonyms: PI3K p110gamma human; Phosphatidylinositol 3-kinase p110gamma human

MDL No.: MFCD03457993

Purity: >=95% (SDS-PAGE)

Activity: activity: ~4.5 units/mg protein

Storage: -70C

UNSPSC Code: 12352207

Biochem/physiol Actions: PI 3-kinases have been implicated in diverse cellular responses triggered by mammalian cell surface receptors. Inhibits NF-kappaB, AP-1, and STAT1alpha mediated gene expression induced by IFN-gamma resulting in inhibition of COX-2 and NOS ll (iNOS) expression.

Physical form: Solution in 10 mM HEPES, pH 7.5, 100 mM NaCl, 0.5 mM MgCl2, 50% glycerol.

Unit Definition: 1 unit will transfer 1 nmol of phosphate/min, using phosphatidylinositol as substrate.