Peptidyl Arginine Deiminase from rabbit skeletal muscle, buffered aqueous glycerol solution, >=200 units/mg protein (Bradford)

Synonyms: Protein arginine iminohydrolase

CAS Number: 75536-80-0

MDL No.: MFCD00165226

Storage: -70C

Enzyme Commission (EC) Number: 3.5.3.15  ( BRENDA | IUBMB )

UNSPSC Code: 12352204

General description: Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline.

Application: Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis.

Biochem/physiol Actions: Calcium is required for peptidylarginine deiminase activity in vitro.

Physical form: Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol

Unit Definition: One unit will produce 1 mumole of N-alpha-benzoylcitrulline ethyl ester from BAEE per hr at 55 C at pH 7.2.